CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia
نویسندگان
چکیده
منابع مشابه
Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin
P2X4 receptors are adenosine triphosphate (ATP)-gated cation channels present on the plasma membrane (PM) and also within intracellular compartments such as vesicles, vacuoles, lamellar bodies (LBs), and lysosomes. P2X4 receptors in microglia are up-regulated in epilepsy and in neuropathic pain; that is to say, their total and/or PM expression levels increase. However, the mechanisms underlying...
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ژورنال
عنوان ژورنال: Purinergic Signalling
سال: 2012
ISSN: 1573-9538,1573-9546
DOI: 10.1007/s11302-011-9288-x